- Selegiline Hydrochloride
Selegiline Hydrochloride 5mg
Brand Name: Eldepryl®
Selegiline prevents the breakdown of a chemical in your brain called dopamine (DO pa meen). Low levels of this chemical are associated with Parkinson's disease.
Selegiline is used together with other medicines to treat symptoms of Parkinson's disease.
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Other Known Brand Names for Eldepryl
- Eldepryl (Draxis Health)
- Eldepryl (I) (Themis Chemicals Ltd.)
- Elegelin (Sun Pharmaceutical Industries Ltd.)
- Jumex (Sanofi Aventis)
- Selerin (Cipla Limited)
- Selgin (Intas Pharmaceuticals Pvt. Ltd.)
- Zelapar (Valeant Pharmaceuticals International)
- Selegiline Hydrochloride
Take selegiline exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor. Larger doses will not have any greater effect, but serious side effects could result. Follow the directions on your prescription label.
While you are using selegiline and for 14 days after you stop, you must not eat foods listed in the "What should I avoid while using selegiline?" section. Eating these foods while you are using selegiline can raise your blood pressure to dangerous levels.
Foods that you MAY eat include:
- fresh meat, poultry, or fish (including lunch meat, hot dogs, breakfast sausage, and cooked sliced ham);
- any vegetables except broad bean pods (fava beans);
- processed cheese, mozzarella, ricotta, cottage cheese;
- pizza made with cheeses low in tyramine;
- soy milk, yogurt; or
- Brewer's or baker's yeast.
Selegiline capsules are usually taken twice a day, at breakfast and lunch. Follow your doctor's instructions.
The disintegrating tablet form of selegiline (Zelapar) should be taken once a day before breakfast and without any liquid.
To take selegiline orally disintegrating tablets (Zelapar):
Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.
Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.
Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves.
Do not drink or eat anything for at least 5 minutes after taking a Zelapar orally disintegrating tablet.
Parkinson's disease is often treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. When you start taking selegiline, your doses of the other medications may need to change. Do not change your doses or medication schedule without advice from your doctor.
Do not stop taking selegiline suddenly or you may have harmful side effects. For best results, keep taking the medicine as prescribed.
Store this medicine at room temperature away from moisture and heat.
What should I avoid while using selegiline
You must NOT eat foods that are high in tyramine, including:
- air dried meats, aged or fermented meats, sausage or salami (including cacciatore and mortadella), pickled herring, and any spoiled or improperly stored beef, poultry, fish, or liver;
- beer from a tap, beer that has not been pasteurized;
- aged cheeses, including blue, boursault, brick, brie, camembert, cheddar, emmenthaler, gruyere, parmesan, romano, roquefort, stilton, and swiss;
- over-the-counter supplements or cough and cold medicines that contain tyramine;
- sauerkraut, soy beans, soy sauce, tofu, miso soup, bean curd, fava beans; or
- yeast extracts (such as Marmite).
Eating tyramine while you are taking selegiline can raise your blood pressure to dangerous levels which could cause life-threatening side effects.
You should become very familiar with the list of foods to avoid while you are taking selegiline.
Avoid drinking alcohol while taking selegiline.
Selegiline can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Usual Adult Dose for Parkinson's Disease
Adjunct to levodopa/carbidopa:
Oral tablet: 5 mg twice a day at breakfast and lunch.
Oral disintegrating tablet: 1.25 mg once a day, before breakfast, for at least 6 weeks. After 6 weeks, the dose may be increased to 2.5 mg once a day if needed.
Usual Adult Dose for Depression
Major Depressive Disorder:
Initial: Apply one transdermal patch (6 mg/24 hours) to intact skin once every 24 hours.
Maintenance: 6 mg/24 hours up to a maximum of 12 mg/24 hours.
Disclaimer: Information and data on Selegiline Hydrochloride (generic Eldepryl®) found on this website is for informational purposes only. This information does not constitute legal advice and it is recommended to first check all information with your medical practitioner.